
绘制杜仲化学成分'资源图谱',发现抗神经炎症三萜。
高锦明,西北农林科技大学化学与药学院教授,从2000年起带领团队跨界开展杜仲化学成分研究,是西农三代'杜仲军团'中承前启后的关键人物。他利用高效液相色谱等现代分析技术绘制出杜仲化学成分的'资源图谱',让杜仲叶、皮、花、籽的科学开发有了简明指南,改变了过去'只售一张皮'的粗放利用模式。
其团队从杜仲叶中首次分离出具有抗神经炎症作用的特殊降三萜成分,为杜仲叶功能食品开发和神经退行性疾病预防开辟了新方向。作为主要完成人参与的'杜仲新品种选育与次生代谢物深度开发利用'获2017年度陕西省科学技术一等奖。他的工作支撑略阳县形成涵盖胶、药、食、饲的杜仲全产业链,年产值超1.2亿元。
Mapped the chemical-component 'resource atlas' of Eucommia and discovered anti-neuroinflammatory nor-triterpenes.
Gao Jinming is a professor at the College of Chemistry and Pharmacy, Northwest A&F University. Since 2000 he has led his team in cross-disciplinary research on the chemical components of Eucommia, serving as a key link between generations of Northwest A&F's three-generation 'Eucommia Corps'. Using modern analytical techniques such as HPLC, he mapped a 'resource atlas' of Eucommia's chemical components, giving the scientific development of Eucommia leaves, bark, flowers and seeds a concise guide and changing the past crude utilization model of 'selling only the bark'.
His team was the first to isolate special nor-triterpene constituents with anti-neuroinflammatory activity from Eucommia leaves, opening a new direction for Eucommia-leaf functional foods and the prevention of neurodegenerative diseases. As a major completer of 'Breeding of new Eucommia varieties and in-depth development and utilization of secondary metabolites', he won the 2017 Shaanxi Provincial Science and Technology Award (First Prize). His work has supported Lueyang County in forming a Eucommia whole industry chain spanning rubber, medicine, food and feed, with an annual output value exceeding 120 million yuan.