梅其炳
Mei Qibing
人物简介
杜仲抗骨质疏松药理研究代表学者，Bone期刊论文通讯作者
事迹
梅其炳是第四军医大学药理学教授，我国骨药理研究知名学者。2009年其团队在骨科学权威期刊Bone发表研究，证实杜仲皮提取物（300-500mg/kg连续16周）可显著防止去卵巢大鼠骨量丢失、改善骨小梁微结构且无子宫增生副作用，被国际同行广泛引用，是杜仲抗绝经后骨质疏松研究的经典文献。
他主持国家自然科学基金项目，系统研究杜仲木脂素与续断皂苷的抗骨质疏松物质基础与配伍机制，提出杜仲叶提取成分可用于防治骨质疏松，并参与秦巴山区中药发展协同创新，推动杜仲资源保护与产业转化。
重要活动 / 事件
- 2012年9月参与组建秦巴山区中药发展协同创新中心，公开阐释杜仲叶提取成分治疗骨质疏松的价值
- 长期任第四军医大学药理教研室教授，兼任西北工业大学生命学院合作导师
代表贡献
- 主持国家自然科学基金面上项目81073037《续断、杜仲抗骨质疏松作用的药理学基础研究》（33万元，2011-2013）
- 通讯作者论文《杜仲皮提取物防治去卵巢大鼠骨质疏松》发表于Bone（2009年第45卷，被引140余次）
- 通讯作者发表杜仲总木脂素抗骨丢失研究于J Ethnopharmacol（2014年第155卷）
- 发表综述《杜仲防治骨质疏松症的研究进展》（《化学与生物工程》2013年第30卷）
Profile
Representative scholar in Eucommia anti-osteoporosis pharmacology research; corresponding author of a paper in Bone
Story
Mei Qibing is a professor of pharmacology at the Fourth Military Medical University and a renowned Chinese scholar in bone pharmacology. In 2009, his team published a study in the authoritative orthopedics journal Bone demonstrating that Eucommia bark extract (300–500 mg/kg for 16 consecutive weeks) significantly prevented bone loss in ovariectomized rats and improved trabecular microarchitecture without uterotrophic side effects. Widely cited by international peers, it is a classic paper in research on Eucommia against postmenopausal osteoporosis.
He led a National Natural Science Foundation project systematically investigating the material basis and compatibility mechanisms of Eucommia lignans and Dipsacus saponins against osteoporosis, proposed that Eucommia leaf extract constituents could be used to prevent and treat osteoporosis, and participated in collaborative TCM innovation in the Qinba Mountain region, promoting Eucommia resource conservation and industrial translation.
Milestones
- In September 2012, participated in establishing the Qinba Mountain Region TCM Development Collaborative Innovation Center, publicly explaining the value of Eucommia leaf extract constituents for treating osteoporosis
- Long served as professor in the Department of Pharmacology at the Fourth Military Medical University and concurrently as a co-supervisor at the School of Life Sciences, Northwestern Polytechnical University
Key Contributions
- Led NSFC General Program project 81073037, 'Pharmacological Basis of the Anti-Osteoporosis Effects of Dipsacus (Xuduan) and Eucommia' (RMB 330,000, 2011–2013)
- Corresponding author of the paper on Eucommia bark extract for preventing and treating osteoporosis in ovariectomized rats, published in Bone (2009, Vol. 45; cited over 140 times)
- Corresponding author of a study on total lignans of Eucommia against bone loss, published in the Journal of Ethnopharmacology (2014, Vol. 155)
- Published the review 'Research Progress on Eucommia in the Prevention and Treatment of Osteoporosis' (Chemistry & Bioengineering, 2013, Vol. 30)
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