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周

周春山

Zhou Chunshan

中南大学教授,杜仲活性成分提取分离
Professor, Central South University; extraction and separation of Eucommia active components
现代科学
Modern Science

人物简介

杜仲桃叶珊瑚苷、绿原酸提取工艺研究先驱

事迹

周春山,1940年生,中南大学化学化工学院教授、博士生导师。2000年代初,他带领团队系统开展杜仲有效成分的提取分离研究:与彭密军等合作研究杜仲中桃叶珊瑚苷的提取工艺,指导完成杜仲中松脂醇二葡萄糖甙的提纯、杜仲叶绿原酸和黄酮的酶法及半仿生法提取等系列工作,成果发表于《林产化学与工业》《精细化工》《中南工业大学学报》等期刊。

他还建立了液相色谱分离制备杜仲环烯醚萜类化合物的方法体系,为杜仲环烯醚萜单体的规模化制备提供了技术路线。其团队研究成果被杜仲加工领域广泛引用,是杜仲化学成分工程化提取研究的早期开拓者之一。

重要活动 / 事件

  • 2000年代带领中南大学化学化工学院团队持续开展杜仲有效成分提取分离研究
  • 其杜仲提取工艺论文被后续研究广泛引用

代表贡献

  • 2003年指导团队在《林产化学与工业》发表杜仲中桃叶珊瑚苷的提取工艺研究,奠定杜仲环烯醚萜苷提取基础
  • 2006年发表酶法及半仿生法提取杜仲叶中绿原酸和黄酮研究(《精细化工》)及杜仲叶绿原酸不同提取方法比较研究(《中国生化药物杂志》)
  • 建立液相色谱法分离制备杜仲环烯醚萜化合物的分析制备体系
  • 培养的杜仲提取方向学生成为吉首大学杜仲研究骨干

Profile

A pioneer in extraction processes for aucubin and chlorogenic acid from Eucommia.

Story

Zhou Chunshan, born in 1940, is a professor and doctoral supervisor at the School of Chemistry and Chemical Engineering, Central South University. In the early 2000s he led his team in systematic research on the extraction and separation of Eucommia active components: collaborating with Peng Mijun and others on the extraction process of aucubin from Eucommia, and supervising a series of works including the purification of pinoresinol diglucoside from Eucommia and the enzymatic and semi-bionic extraction of chlorogenic acid and flavonoids from Eucommia leaves, published in journals such as Chemistry and Industry of Forest Products, Fine Chemicals and the Journal of Central South University of Technology.

He also established a liquid chromatography method system for the separation and preparation of Eucommia iridoid compounds, providing a technical route for the large-scale preparation of Eucommia iridoid monomers. His team's results are widely cited in the Eucommia processing field, making him one of the early pioneers of engineered extraction research on Eucommia chemical components.

Milestones

  • In the 2000s, led his team at the School of Chemistry and Chemical Engineering, Central South University, in sustained research on the extraction and separation of Eucommia active components
  • His papers on Eucommia extraction processes have been widely cited by subsequent research

Key Contributions

  • In 2003, supervised his team in publishing research on the extraction process of aucubin from Eucommia in Chemistry and Industry of Forest Products, laying the foundation for the extraction of Eucommia iridoid glycosides
  • In 2006, published research on enzymatic and semi-bionic extraction of chlorogenic acid and flavonoids from Eucommia leaves (Fine Chemicals) and a comparison of different extraction methods for chlorogenic acid from Eucommia leaves (Chinese Journal of Biochemical Pharmaceutics)
  • Established a liquid chromatography system for the separation and preparation of Eucommia iridoid compounds
  • Students he trained in Eucommia extraction became backbone researchers of Eucommia studies at Jishou University
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